Bernadette Soubirous (Jennifer Jones) is a sickly 14-year old girl who sees a vision of a "beautiful lady", and never suffers from her illness again. Moreover, a fountain suddenly materialises near her vision that seems to heal visitors who bathe in it. Unspoiled by her apparent gift, Bernadette nonetheless suffers the prejudices of those around her in this extraordinary, inspiring film that also stars Vincent Price, Charles Bickford and Lee J. Cobb.

Jennifer Jones won the Academy Award for Best Actress in her screen debut. The film also won Oscars in 1943 for Best Cinematography, Music (Scoring) and Art Direction/Interior Decoration.

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