Super-spy Ethan Hunt (Tom Cruise) has retired from active duty to train new IMF agents. But he is called back into action to confront the toughest villain he's ever faced - Owen Davian (Philip Seymour Hoffman), an international weapons and information provider with no remorse and no conscience. Hunt assembles his team - his old friend Luther Strickell (Ving Rhames), transportation expert Declan (Jonathan Rhys Meyers), background operative Zhen (Maggie Q), and fresh recruit Lindsey (Keri Russell) - to travel the globe pursuing Davian and rescue Hunt's love, Julia (Michelle Monaghan).