After a horrifying PredAlien crash-lands near a small Colorado town, killing everyone it encounters and producing countless Alien offspring, a lone Predator arrives to "clean up" the infestation. Soon it's an all-out battle to the death with no rules, no mercy - and hundreds of innocent people caught in the crossfire. As the creature carnage continues, a handful of human survivors attempt a daring escape, but the U.S. government may be hatching a deadly plan of its own...